He also missed the majority of two practice sessions on Friday with a nasty vibration in the car.
Prodrive Racing have now won eight races from 16 starts this season and yesterday's result saw Winterbottom jump out to a commanding 176-point lead over Coulthard, who leapfrogged Holden's Craig Lowndes in the standings after the Red Bull Racing driver finished 14th.
Coulthard's performance was also impressive, improving from eighth on the grid to the podium and he even threatened Winterbottom and Reynolds in the final 10 laps of the race.
"I drove the wheels off it," Coulthard said. "The strategy was awesome, Phil [Keed] my engineer was coaching me the whole way. He was a little bit stressed there with the way I was murdering the tyres in the early stages, but we made it in the end."
Winterbottom started from second on the grid alongside team-mate Chaz Mostert and grabbed the lead at the first corner in his Falcon FG X.
"That was awesome," he said. "We pushed the tyre and there was nothing left at the end. To see Dave second " at the end he was really close and I thought he might've had a go. To have a team one-two was awesome. It's a well-earned one. It's a tough race."
Defending champion Jamie Whincup continued to struggle, finishing ninth.
"It was an improvement on his recent finishes but he's still well off the pace in the championship standings.
Mostert faded late to finish eighth, also giving up crucial points to Winterbottom in the title race.
The Townsville 400 wraps up today with another 200km race.