"I think we've got a strong driver line up, a strong team and a strong car, so I'm looking forward to the event."
Lowndes won the race earlier this year and is excited about his chances of a repeat victory.
"The Bathurst 12 Hour is one of my absolute favourite events, so I am delighted to have the chance to defend my win in 2017 but in a McLaren for the first time," said Lowndes.
"McLaren is an iconic name in motor racing and the 650S is a serious bit of kit, so I am really excited about the opportunity to race it at Bathurst with Shane (Van Gisbergen) and Côme (Ledogar). I can't wait."