But scaling the heights of professional football hasn't been Uiagalelei's only dream. Like Murray, who was selected by Arizona at pick No. 1 in this year's NFL Draft, his freakish gifts also carry over to baseball. The same arm that makes him so dangerous at quarterback also gives him the ability to pitch a fastball at 150km/h.
The No. 1 ranked quarterback in the country for the 2020 class still wants to play baseball at college and his high school baseball coach Don Barbara said if he wanted to, Uiagalelei could make it to the majors in no time.
"It really was unbelievable," Barbara told Bleacher Report. "I don't think it would take him that long to get to the big leagues. Not with his arm and not with his curveball.
"I hear from agents and from scouts. There are a lot of people interested in him. If that guy was pitching right now, the stadium would be filled. It's crazy."
But while he's got the raw skills to dominate from the mound and an MLB career down the line isn't out of the question, it seems his immediate future lies on the football field.
Recruiting analyst Greg Biggins told Sports Illustrated Uiagalelei is "scary" and, writing for 247Sports.com, he offered up a glowing review of his skill-set and attitude.
"Big, strong armed quarterback with generational arm strength," Biggins wrote. "Has one of the strongest arms in recent memory.
"Shows great touch, accuracy to all three levels of the field and great natural feel for throwing the football. Understands when to take a little off, throws with anticipation and is a plus athlete as well.
"Natural leader and a great teammate who is also a potential high round draft pick in Major League Baseball.
"Can still improve going through progressions and finding secondary receivers as well as escaping pressure. Upside is off the charts."
247Sports director of scouting Barton Simmons is equally in awe of what Uiagalelei can become.
"It's all about pure physical traits for DJ," he said. "There's a really high floor, low bust potential for a guy that is as gifted from an arm and frame standpoint as DJ is.
"The production matches, the accuracy is there and we've really seen his game evolve over the last year or two. So there's reason to believe he's just getting started."
If he does progress to the NFL, there's every chance Uiagalelei could one day be joined by his younger brother Matayo. At just 14, Matayo has several scholarship offers of his own and has already benefited from Big Dave's monstrous physique, weighing over 100kg and standing as tall his older sibling.
But for now all eyes are on DJ and wherever he chooses to go to college — be it Clemson or Oregon — you can bet the eyes of hungry NFL scouts will follow.
