Leaders Saracens accounted for Sale 28-13. Sam Tuitupou, Bryn Evans, Halani Aulika and TJ Ioane all appeared for the Sharks.
In the French Top 14, Tom Donnelly's Bayonne caused a boilover, edging Luke McAlister's Toulouse 16-13.
Zak Taulafo's Stade Francais beat Montpellier 21-17.
Bordeaux-Begles' ascent continued with a 26-0 shutout of La Rochelle. Simon Hickey kicked five goals for the victors, and loose forwards Luke Braid, Hugh Chalmers and Joe Edwards all featured. Romana Graham, Jason Eaton and Victor Vito played for the visitors.
William Whetton's Brive accounted for Pau 38-25. Chris King scored a try for the latter, while Tom Taylor kicked two goals. Jamie Mackintosh and Daniel Ramsay also started in the Pau pack.
Clermont, with Hosea Gear, Benson Stanley and Fritz Lee (who was sinbinned) in the line-up, edged Lyon 16-13. Ti'i Paulo, Rudi Wulf and Toby Arnold started for Lyon.
David Smith's Castres defeated Ma'a Nonu's Toulon 34-17.
Racing-Metro beat Grenoble 29-24. Starting for the Parisians were Joe Rokocoko and Anthony Tuitavake, while former Waikato No 8 Rory Grice was on the back of the visitors' scrum.
Round nine of both the Aviva Premiership and Guinness PRO12 take place this weekend, while the French Top 14 breaks for a week for the final few days of the November international window.