Christie Kerr, the winner in 2008 the last time the event was played at Columbia Edgewater, was at 66 along with Lizette Salas and Germany's Sandra Gal.
Second-ranked Stacy Lewis, returning to play after withdrawing from the Canadian Women's Open last week because of illness, opened with a 67.
Hall of Famers Juli Inkster and Se Ri Pak also were in the large group at 67 that included Michelle Wie, Yani Tseng and Ai Miyazato. The 53-year-old Inkster won the last of her 31 tour titles in 2006.
Natalie Gulbis had a hole-in-one on the second hole and finished with a 68.
Suzann Pettersen, the 2011 winner, also shot 68.
Defending champion Mika Miyazato opened with a 71.
Top-ranked Inbee Park withdrew Tuesday because of illness.