Eric Bautheac was strong through the middle, and Matt McKay's distribution created chances for Fahid Ben Khalfallah in behind Wellington's defence.
Thomas Kristensen and Brett Holman also looked dangerous from a distance, but their long-range strikes lacked accuracy, and the two teams went into the break scoreless.
The Nix manufactured a few decent chances, but strong strikes from Monty Patterson, Nathan Burns and Liberato Cacace were all blocked by desperate Roar defence.
However, it took Brisbane just five minutes from the restart to seize the lead.
Massimo Maccarone's cross found Holman in plenty of space, and the 33-year-old veteran provide a composed finish to volley home past Oliver Sail for his fifth goal of the season.
Wellington responded clinically three minutes later through Andrija Kaludjerovic before Logan Rogerson gave them an unlikely 2-1 lead after 65 minutes.
Kaludjerovic nailed his ninth goal of the season courtesy of a beautifully weighted through ball from Matija Ljujic, Rogerson climbing high 10 minutes later to nod home Nathan Burns' cross.
Brisbane equalised just three minutes later, Maccarone's header rebounding kindly for Kristensen to prod home.
Burns came close to sealing the win for Wellington with an 88th minute thunderbolt but Roar keeper Jamie Young delivered a top-drawer save in tipping the strike onto the crossbar to leave the scores level.
-AAP