The hosts have won the last four against the Phoenix, going back to October 2011 and including the 3-2 loss at Etihad Stadium last October when All Whites and former Phoenix striker Marco Rojas scored either side of halftime to lay the foundation.
In that game, Jeremy Brockie scored twice late in the game - his first two goals of the season and the launching pad for the 10 he has now scored to join Daniel McBreen at the top of the golden boot. Brockie leads the season shot count with 41, five more than McBreen.
But Herbert, who has now overtaken former Victory coach Ernie Merrick as the coach in charge of most A-League matches, will be more concerned with a result than statistics.
While he will stick with his long-established defensive quintet, he must make calls in the midfield and on attack in replacing Muscat and Boyd.
Belgian Stein Huysegems could win a starting slot, ahead of the exciting Benjamin Totori, alongside Brockie and Louis Fenton up front. Alex Smith or Cameron Lindsay could be in line for Muscat's midfield spot.
Lindsay has been with the team from the outset of this two-match trip while Smith left the field after coming on as a substitute against Brisbane. The team were joined on Thursday by defender Michael Boxall even before Muscat's case went before the judiciary.
Smith was later cleared of what was a suspected fractured cheekbone and could regain the spot he surrendered to Dani Sanchez in the attacking midfield role a few weeks ago.
Perilously close to dropping well outside the top six, the Phoenix will again keep tabs on other 15th round games this weekend, especially the second of three games today when Sydney FC travel to play Perth Glory.
In tomorrow's match of the round, new boys Western Sydney Wanderers entertain leaders Central Coast Mariners.
The Mariners hold a two-point lead over Adelaide who are away to Newcastle in today's early game.
A-League
Melbourne Victory v Wellington Phoenix
AAMI Stadium, Melbourne
9.45pm, SS2