PSG's priority had been to persuade Mbappe to sign but the sudden availability of Messi – and with Manchester City stepping away from the deal – has led to them considering whether they can make the move work financially.
Sources have suggested that Manchester United may also have shown some interest in signing Messi but it appears negotiations have moved quickly with his father, Jorge, over the past 24 hours and PSG are now firmly the favourites.
City manager Pep Guardiola has publicly ruled his club out of making a move for Messi – and this has been backed up privately by sources - while Barcelona president Joan Laporta made it clear on Friday that the announcement the forward was leaving was not an act of brinksmanship aimed at the salary limits imposed by La Liga.
Messi, Barcelona's all-time leading goalscorer, had agreed a new five-year contract on reduced wages - but the club still had to slash their wage bill to afford him, and were unable to do so.
"Leo wanted to stay, so he's not happy," Laporta said. "We all wanted him to stay. For him, he has to confront reality. It's a reality that can't be changed and he knows I wish him the best wherever he goes."
Laporta added that he did not want to give "false hope" on "hypothetical" ideas that would see keeping Messi possible. "This negotiation has ended," he said.
It now appears PSG will be his destination.