They have accumulated just 11 points from nine matches in the English Premier League and have three draws from three Europa League matches, all from winning positions.
“Erik ten Hag has left his role as Manchester United men’s first-team manager,” United said in a statement.
“Ruud van Nistelrooy will take charge of the team as interim head coach, supported by the current coaching team, whilst a permanent head coach is recruited.”
With British billionaire and Ineos chairman Sir Jim Ratcliffe taking over football operations last season, the club initially stuck with Ten Hag to ensure continuity in the manager’s position during a time of change.
But Sunday’s 2-1 league loss at lowly West Ham United, in which Ten Hag’s side failed to capitalise on numerous chances, only increased the media speculation that he would be sacked.
United finished last season with a surprise FA Cup final win over Manchester City and Ten Hag pointed to the team’s numerous injuries to help explain their poor form.
He signed a new contract to extend his stay until 2026 and was given another chance to restore the 20-times English league champions to former glories.
United’s woeful start to this season has come despite more than $1.1 billion being spent on new players since Ten Hag took charge ahead of the 2022-23 campaign.