Pattinson made his return to test
cricket in the 251-run win at Edgbaston. He collected just two wickets in that game and, although not injured, Australia chose to rest him for the second game because of his history of back problems.
The series-opener was Pattinson's first test in more than three years.
His absence leaves what appears to be a straight choice between Starc and Hazlewood. Australia could recall both and rest Peter Siddle.
England is expected to give a test debut to quick Jofra Archer in place of the injured James Anderson. Archer played a starring role in England's World Cup triumph last month.