Durant was the game's top scorer with 22 points to go with eight rebounds.
The Thunder's 40-point victory was just five points shy of a franchise record for margin of victory.
Los Angeles Lakers retiring legend Kobe Bryant missed the clash with a sore right shoulder, but he said he doesn't believe it's serious and that he should be able to play on Tuesday against the Nuggets in Denver.
Meanwhile, Ellie Day, the wife of Australian golf star Jason Day, still has concussion symptoms despite being released from hospital after being fallen upon by LeBron James while sitting courtside at Cleveland's win over the Thunder last week.
Day, who gave birth to the couple's second child last month, was taken out on a stretcher after James tumbled into her while chasing a loose ball in the fourth quarter of Thursday's 104-100 victory over Oklahoma City.