Tiffany Townsend secured another American victory in the 200, winning in 22.77 ahead of compatriot Charonda Williams and Kerron Stewart of Jamaica. Another American, Natasha Hastings, was fourth.
Three-time world champion Robert Harting delighted his hometown fans by winning the discus with a throw of 69.02 meters.
Harting was pushed hard by compatriot Martin Wierig, who threw 66.73 meters.
"I didn't think it was fair that Martin threw so far," Harting joked. "But I take it as healthy competition. He woke me up."
Poland's Robert Urbanek and Piotr Malachowski were third and fourth, respectively.
There were more cheers among the 55,000 fans at the Olympic Stadium for Germans Christian Reif and David Storl, who claimed victories in the long jump and shot put, respectively.
Hillary Kipsang Yego of Kenya claimed victory in the men's 3,000 steeplechase in 8 minutes, 8.84 seconds, while Turkey's Ilham Tanui Ozbilen won the 1,500 in 3:35.58 and Mohammed Aman of Ethiopia claimed the 800 in 1:43.97.
"The result is all right," said Aman, the only one of three individual world champions to claim victory.
Russia's Maria Abakumova set a meet record of 70.53 meters to win the javelin, ahead of Linda Stahl of Germany and the German world champion Christina Obergfoell.
"I have to admit that I am thinking about the world record now. My family and my whole team help me believe I can make this dream come true," Abakumova said with an eye on Barbora Spotakova's mark of 72.28 meters set by the Czech in 2008.
Olympic and world champion Valerie Adams of New Zealand claimed the women's shot put with a throw of 20.58 meters.
"This was my last competition of the year and I am pretty tired," Adams said. "But I am still happy with my shape."
