The chief injury concern as Gatland mulls his selection will be lock Cory Hill, who has a leg fracture that may keep him out until the third pool match against Australia in Tokyo. Ross Moriarty is expected to feature despite pulling out of Saturday's defeat before kick-off due to a hip complaint. Whichever individuals make the cut, Gatland will be confident.
"I think it's the best squad in terms of the depth we've got," he added. "We've got an excellent forward group, some real leadership and experience.
"We have some nines that are continuing to develop. If we do pick up a few injuries like we did in 2015, I think we'd be able to cope so much better now.
"The expectation from ourselves is that we'll be very disappointed if we don't make the quarter-finals and that's step one."
Gatland had billed the Ireland encounter as a shoot-out for the second of two fly-half slots, with Jarrod Evans starting and Rhys Patchell among the replacements. Patchell arrived at half-time and made a number of bright contributions, including a tackle on Chris Farrell that forced a spill in the shadow of Wales' posts and a well-taken try that gave the hosts a chance of an unlikely comeback win.
The role of Dan Biggar's deputy will be one of "probably six positions" to be debated tonight, but Gatland did not suggest that Evans' early exit would prove terminal for his Rugby World Cup prospects.
"There's no doubt that Rhys came on and did a good job," Gatland added. "But it's a hell of a lot easier coming off the bench when there's no pressure on you.
"It was hard for Jarrod in the first half when the team isn't going as well as it could."