Four people suffered minor injuries after a crash at Gibbston near Queenstown this morning.
The two-vehicle accident is the second this week on the 100km/h stretch of State Highway 6 through the wine valley.
Firefighters were called to the junction with Gibbston Valley Winery about 11am. One person had to be freed from a vehicle.
Station Officer Nathan Clark of the Arrowtown Fire Brigade said the crash involved a privately owned campervan heading towards Queenstown and a car turning into the winery.
"One lady had to be extracted. She's wasn't trapped but was uncomfortable, so we popped the doors off."
The 15-minute operation involved about 25 members of the emergency services, including the Arrowtown, Frankton and Queenstown brigades, along with police and St John.
Both vehicles sustained significant damage. They spun together in the crash and ended up wedged against the winery's stone wall.
All four people involved were believed to be tourists.
On Tuesday, six cars were involved in a shunt accident about half a kilometre down the road near the AJ Hackett Bungy Centre bridge over the Kawarau River. No one was injured.
Mr Clark said: "There's been a few [accidents] in recent years and a couple in the past month - just people not paying attention on the roads."