St John Ambulance spokeswoman Noreen Hegarty said the driver of the car was taken to Middlemore Hospital in a serious condition.
She said 12 other people were checked out by paramedics.
None were transported or had serious injuries.
UPDATE: Linwood & Kingseat Rds now CLOSED btwn McKenzie Rd & Batty Rd due serious crash. Allow extra time for diversions ^TP pic.twitter.com/0ChbT3QOUu