St John said two people were transported to Taranaki Base Hospital in New Plymouth, one in serious condition and the other in moderate condition.
Police received a report at 4.45pm that a car has crashed into a building, a Police spokesperson said.
Further north, Police responded to a crash involving a motorbike and a car at around 4pm in Maungaturoto.
The crash happened on Bickerstaffe Rd, a Police spokesperson said.
"Ambulance and FENZ are also responding," the spokesperson said.
"It appears a person has been transported to a rescue helicopter."
St John said one person was transported via helicopter to Northland Base hospital in Whangārei in moderate condition.
In the Far North, a person was injured by a tractor in Mangonui.
Police were called to the scene at on Midgley Rd at around 4.05pm.
An ambulance also attended to assess the person and injury was not serious, a Police spokesperson said.