Police serious crash unit investigators were still at the scene this evening. A detour would remain in place until further notice.
An Otago Daily Times reporter at the scene said the crash involved a truck and trailer and a campervan, at the bottom of a steep hill near Wanaka Airport.
A St John spokesman said emergency services were alerted at 4.14pm and sent an ambulance and the Otago Regional Rescue helicopter from Dunedin to the scene.