Police have confirmed there were eight people in the car.
A spokeswoman for St John said they got the call at 4.39am from police.
Two Westpac rescue helicopters and at least three ambulances were sent to the scene.
She confirmed seven people were rushed to hospital, including two in a critical condition. Four others have serious injuries while another is in a moderate condition.
St John later said one of the injured included a 13-year-old girl in a critical condition. Other teenagers were also injured.
A spokesman for Canterbury District Health Board (CDHB) said one patient had already been discharged. One was in a stable condition. Four had requested privacy. The CDHB said it was unable to get the necessary consent or permission to provide an update for the two other patients at this stage.
A police spokesman said: "Inquiries are ongoing to determine the circumstances around the collision."
The police serious crash unit has completed its scene examination and NZTA said the road had reopened by late morning.