The road remains closed, and motorists are advised to delay travel through the area.
“Police do not recommend a detour through Hawksburn Road from Clyde to Bannockburn as it is narrow and unsuitable for 2wd vehicles,” the spokesperson said.
A Hato Hone St John spokesperson earlier said they responded with two ambulances and one manager to the crash on Cromwell-Clyde Road at 6.34am.
The spokesperson said one patient was assessed and treated at the scene, but referred any further inquires to Police.
NZTA Waka Kotahi said the crash was reported just before 7am around 5km east of the town, near the Cromwell Gorge picnic area.