"The incident was disappointing because people are generally respectful at the Nelson market even when they disagree with government policy or my views.
"This incident at the Nelson market comes on the top of deliberate sabotage of the sanctuary fence and the holing of a fuel tank on site for helicopters."
He says the Brook Valley Community Group opposing the pest control needs to condemn these criminal acts.
"This matter has been to court three times, twice in the High Court and a third in the Court of Appeal. The courts have ruled clearly that the pest control operation is lawful.
The regulation and monitoring of the poison is tight and the environmental benefit of a pest-free sanctuary is huge," Dr Smith said.
He said the science was clear that the only way birds like kiwi, kokako, kea and kaka would survive was to effectively control the pests that decimated their populations.
A total of 26.5 tonnes of bait laced with brodifacoum will be dropped in the operation, according to a court judgment.