"Shirley is about 157cm tall, of lean build and has short cropped hair. She was believed to be wearing jeans and a top with a small jacket of unknown colour when she was last seen and we ask anyone that may come into contact with her to try and calmly offer reassurance and to contact Police."
Police believe the fuel tank of Shirley's Ford Taurus was about half full when she left on Thursday giving her an estimated range of 200-300km.
Police are asking the public who have seen the vehicle over the past two days to make contact with them.
"The longer time goes on without contact with Shirley the more concerned her family, and Police become about her well-being."
Anyone who may have come into contact with Shirley Loft or who may have seen her car is asked to contact Whitianga Police on 07 866 4000.