Lengthy diversions - forcing traffic around the western side of Lake Taupo - were originally in place but NZTA has confirmed both lanes of SH1 were re-opened about 4.30pm.
The scene of the crash is also home to a 25kph sign-posted corner and a bridge which crosses the Tauranga Taupo river.
The New Zealand Transport Agency has confirmed SH1 is now open following the crash.
"Emergency services and our contractors have managed to clear the site and both lanes of SH1 are now open," said NZTA spokeswoman Natalie Dixon.
However traffic in the area had built up and motorists were being advised to avoid it if they could.