Opening in stages as work was completed, the Brownston St location would house the lead maternity care midwives, tele-health and rural secondary care clinics.
The space would also be equipped for responding to maternity emergencies and unplanned rapid births, Weathington said.
The hub is part of the Southern District Health Board primary services strategy and similar spaces existed in Te Anau and Lumsden and provides extra support to remote rural communities.
The hub would not be a designated birth space or offer overnight postnatal care, Weathington said.
Wanaka residents could currently birth or stay postnatally at home, at Charlotte Jean Maternity in Alexandra, Lakes District Hospital, Queen Mary Maternity Centre at Dunedin Public Hospital or Southland Hospital in Invercargill.
Weathing said the SDHB continued to evaluate where the best place for Central Otago primary birthing units would be, and a decision was expected later this year.
"Wanaka families and midwives remain hopeful for a primary birthing unit in Wanaka. This unit would provide a designated space for planned low-risk birth and postnatal care closer to home."
The opening week of the hub aligned with the International Day of the Midwife on May 5, she said.