"Mice normally have home ranges of about 50 square metres, but this mouse roamed over at least 500 square metres, at least a quarter of the island," he said.
However, after 61 days of tracking and trapping, the rogue rodent was finally caught at the mouth of a World War II water pipe at Army Bay.
DoC Bay of Islands biosecurity ranger Angela Newport said it was not clear how the male mouse had arrived.
"It's possible it came with illegal campers or with other people using Army or Mangahawea bays," she said.
"At this time we don't know whether it was a sole invader or if there are still other mice on the island. So far the checks have been clear for two weeks.
"We don't want mice ... as insect and bird populations are recovering well without them."
People could help Project Island Song succeed by checking their gear and boats for stowaways before leaving the mainland, she added.