The man, 51-year-old Bradley Selmon, has been exposed to asbestos for many years during his work as a plumber. He was diagnosed with mesothelioma in 2013 and decided to enter Dr Reid's trial after he stopped responding to chemotherapy treatment.
Within two months, his tumours had "virtually vanished.''
"The pain stopped. All of a sudden I could yawn without restriction. Now, I can go bushwalking and walk up steep steps - anything I want to do,'' he said.
Tests showed his lung functionality was now "pretty normal'' and he felt that the trial had saved his life.
Mr Selmon's oncologist - Dr Steven Kao of the Chris O'Brien Lifehouse cancer centre in Sydney - praised the results, saying his patient's mesothelioma was now almost invisible.
Professor Reid's work and results will today be published in the American Journal of Respiratory and Critical Care Medicine.
He said: "If it works in more patients, this treatment has the potential for a paradigm shift in the management of other treatment-resistant tumors.''