The NSX, Honda's highest performance sports car, was last built in 2005 in Japan, where it had been manufactured since 1990.
Honda says the new NSX will feature a lightweight chassis, a mid-mounted V6 engine, a dual-clutch transmission and an all-wheel-drive hybrid powertrain.
Honda R&D Americas chief engineer Ted Klaus, who is leading the global team developing the new NSX, told reporters in a conference call that it will provide "tremendously high performance in response to the driver" and strike the right balance between technology and value.
The new NSX to be built exclusively at the Ohio site will be sold in North America and exported throughout the world.
The company now has 14 manufacturing facilities across North America, producing Honda and Acura vehicles, car engines and transmissions, Honda all-terrain vehicles, lawnmowers and general purpose engines.
-AP