* A Better Start - improving the potential of young New Zealanders to have a healthy and successful life ($34.6 million over 10 years)
* Healthier Lives - research to reduce the burden of major New Zealand health problems ($36.7 million over 10 years)
* Science for Technological Innovation - enhancing the capacity of New Zealand to use physical and engineering sciences for economic growth ($116.5 million over 10 years)
* New Zealand's Biological Heritage - protecting and managing our biodiversity, improving our biosecurity, and enhancing our resilience to harmful organisms ($207.1 million over 10 years)
* Our Land and Water - research to enhance primary sector production and productivity while maintaining our land and water quality for future generations ($227.3 million over 10 years)
* Sustainable Seas - understanding how we can utilise our marine resources within environmental and biological constraints ($146.5 million over 10 years).
The request for proposals for the second batch of challenges will be issued on January 31, with proposals due by the end of April.