"The statistics suggest the observations of increased treatments and large strokes in Christchurch did not occur by chance.
"The most plausible explanation is the generalised stress response after the terror attack. This may increase risk of blood clotting."
Professor Tim Anderson, clinical director of the NZBRI, said the study has been hailed internationally as an exceptional and important piece of work.
"It shows a clear relationship between stress and acute and large strokes. There has never been clinical evidence of this before.
"Worldwide, post-9/11 New York researchers focused on heart failure, and Japanese researchers reported an increased number of strokes throughout Japan at the time of the earthquake/tsunami in 2011, but in terms of having information about the size of the strokes, our study is unique," he says.
Three days after the terror attack, the NZBRI team set out to see if there was an increase in strokes in the city.