The prince has since faced a series of controversies leading sources to brand him a "busted flush" with a "toxic" presence, The Sunday Times reported.
The prince was also widely condemned for his lack of remorse over his friendship with convicted paedophile Epstein.
The interview caused several businesses and charities to cut ties with the prince and forced him to hire PR expert Mark Gallagher to deal with the fallout.
The prince was again thrust into the headlines earlier this month after £355,297 ($705,000) paid to his private secretary, Amanda Thirsk, was branded an "unauthorised trustee benefit".
Andrew is also currently in a dispute alongside his ex Sarah Ferguson over a £6 million ($11.9m) debt on their £18m ($35.7m) ski chalet in Verbier, Switzerland.
The Queen is said to now be paying the debt after a French socialite threatened to drag the case through the courts, it is claimed.