The findings show that every five-kilo decline in grip strength was associated with a 16 per cent increased risk of death from any cause; a 17 per cent greater risk of cardiovascular death; a 17 per cent higher risk of non-cardiovascular mortality and more modest increases in the risk of having a heart attack (seven per cent) or a stroke (nine per cent).
Overall, grip strength was a stronger predictor of all deaths, including those from heart disease, than systolic blood pressure.
The associations persisted even after taking into account differences in other factors that can affect mortality or heart disease such as age, education level, employment status, physical activity level, and tobacco and alcohol use.
Dr Darryl Leong, of McMaster University in Canada, who was the lead author, said: "Grip strength could be an easy and inexpensive test to assess an individual's risk of death and cardiovascular disease.
"Further research is needed to establish whether efforts to improve muscle strength are likely to reduce an individual's risk of death and cardiovascular disease."