Their brains were then scanned for signs of amyloid-beta deposits - the key marker of Alzheimer's disease. The hippocampus, a part of the brain linked to memory, was also examined for signs of shrinkage - another sign of the condition.
The scientists found that although those who engaged in stimulating mental activities had much higher IQs and better thinking skills, there was no relationship between frequent mental activity and the physical signs of Alzheimer's in the brain.
But study co-author Dr Keith A Johnson warned older people not to abandon exercise and puzzles, as although they would not stop the underlying disease, they would still help their brains function.
"Sustaining a lifetime of intellectual engagement may help preserve cognitive function into old age," he added.
- Daily Mail