Khalifa now works as a sports show host and she told disgraced cyclist Lance Armstrong's podcast about the effect the threats had on her.
"It all started to spiral out of control when the death threats from ISIS started coming in. That's when I stepped away," the 25-year-old said, the Daily Star reported.
"As soon as I started to gain popularity that's when I was like 'get the f*** out of this'.
"This was not what I was trying to do whatsoever. I just wanted to let loose and rebel a little bit."
Many took issue with a scene from one of her videos showing her having sex while wearing a hijab, part of traditional female Muslim dress.
Khalifa - who comes from a Christian family - told The Washington Post in 2015 that she was surprised this scene in particular caused anger and was meant to be satirical.
"There are Hollywood movies that depict Muslims in a much worse manner than any scene Bang Bros [the company who made the video] could produce."
