An ongoing feud between Donald Trump and Brzezinski is said to have fuelled the comments, after Trump released a series of tweets about the MSNBC Morning Joe presenter.
Trump described Brzezinski as "low IQ Crazy Mika" and claimed she was "bleeding badly from a facelift" while at his Florida resort for New Year's Eve.
And he didn't stop there, adding: "Crazy Joe Scarborough and dumb as a rock Mika are not bad people, but their low rated show is dominated by their NBC bosses. Too bad!"
When asked about cyber-bulling and Trump's antics, Brzezinski replied: "I know Melania. I haven't talked to her in months, but if my gut is right, I don't think she's going to put up with it much longer. That's just my instinct and I go with my gut and my gut's always right."
