On Sunday, it will be the turn of Marni, Dolce & Gabbana and Giorgio Armani, after which the Armani house will host a glitzy inauguration party for a new exhibition to showcase the Italian designer's most memorable creations.
Fashion week winds up with DSquared2, Roberto Cavalli and Gianfranco Ferre on Monday, with Tuesday dedicated to up-and-coming new designers.
Beneath the frantic pre-show preparations taking place in the city's palaces, parks and historic monuments - including the imposing 14th-century Sforzesco Castle - there is an air of apprehension over the sector's health.
Last week the fashion industry forecast a 5.6 per cent drop in revenue for 2012 to 60.2 billion euros, down from an earlier 5.2 per cent estimate - and luxury brands in the recession-hit country are being squeezed.
While many fashion houses are now focusing their efforts on expansion abroad - particularly in economic powerhouses such as China and Brazil - there are still bids to attract wealthy visitors to Italy's commercial capital.
Fashion week this season will be marked by a string of boutique openings - from Just Cavalli - opening on the exclusive Corso Matteotti with a party on Friday - to British lingerie brand Agent Provocateur.
And in a declared bid to boost Made in Italy, Nicole Minetti, a television starlet-turned-politician on trial for procuring prostitutes for former Italian prime minister Silvio Berlusconi, will model lingerie on the catwalk for Parah according to media reports.
- AFP