"The personality of the author leaps from these pages and we are treated to a remarkable insight into her creative genius."
In one of the annotations, Rowling adds the words "changed my life forever" to the book's title.
She also questions whether a badger to represent Hufflepuff, one of the four houses at Hogwarts School of Wizardry and Witchcraft where Harry studies, was the right choice.
Rowling writes: "Perhaps Hufflepuff would have the respect it deserves from fans if I'd stayed with my original idea - a bear to represent it?"
Among the edition's original drawings is one of the orphaned baby Harry wrapped in blankets and left on a doorstep with a note.
After the first book was published in June 1997, the Harry Potter series went on to sell more than 400 million copies worldwide
It was transformed into a blockbuster film franchise starring some of British acting's finest talent and saw Rowling become what Forbes magazine described as "the first billion-dollar author".
The auction will take place on Tuesday.
- AAP