At the advanced stage, kidney failure often develops and even with treatment, death may be inevitable.
Early vigorous treatment is essential for survival as metabolic changes become irreversible towards the later stages of the disease.
In early stages, oral treatment with an energy supplement like KetoAid or Ketol may be sufficient to raise blood glucose levels, but more severe cases may require an intravenous injection of suitable medications given by the vet.
Plenty of easily accessible feed and water should be offered and grazing should be encouraged.
In some cases, a caesarean section is done to remove the lambs or kids from the uterus and reduce the metabolic drain on the ewe or doe during pregnancy.
As always prevention is better than cure, so avoid sudden changes in feed levels and provide plenty of good quality feed for pregnant ewes and does.
Take care when yarding animals for shearing or other reasons and have them yarded for as little a time as possible so ewes can get back to grazing quickly. Reduce stocking rates during pregnancy, maybe moving rams, lambs or dry stock off the property, and consider getting ewes scanned to detect which are carrying multiple lambs so these can then be preferentially fed.
It is also important to prevent liver damage from facial eczema by using zinc bullets in summer during the FE risk period.
If you are concerned about your pregnant ewes or does developing sleepy sickness, call your vet sooner rather than later. The sooner we can provide treatment, the better the outcome is likely to be.