The star doesn't totally rule it out but thinks it's highly unlikely she will ever have a procedure.
"Cosmetic surgery is getting so common now and can be scary - it's sometimes like looking at someone wearing a mask,'' she mused.
"I haven't had anything done yet, but maybe I'll hit 70 and think it's time to have something done. I would never, ever use Botox, though. It's poison. It's basically botulism - why would you inject your face with that? I can't understand it.''
Twiggy also discussed the world in general. She worries about how hard young people have it nowadays, especially with university fees rising in the UK.
"The state of the world is so scary at the moment and I think, when I was starting out, we had a much easier time than youngsters now,'' she said.
"It's terrible that kids are leaving university and not getting jobs. It really troubles me. I wish there was a magic answer.''
- AAP