But the jury selection paints a grim picture about how people view Shkreli, who is known for raising the price of Aids drug Daraprim by 5000 per cent and for buying a rare Wu-Tang Clan album for a rumoured $2 million and refusing to release it.
"The purpose of jury selection is to ensure fairness and impartiality in this case. If you think that you could not be fair and impartial, it is your duty to tell me. All right. Juror Number 1," the judge states.
Juror Number 1 replied: "I'm aware of the defendant and I hate him ... I think he's a greedy little man."
Another potential juror dismissed by the judge said: "Totally he is guilty and in no way can I let him slide out of anything".
A third simply called him "a snake".
View some of the transcripts below: