"Do you want to keep pooping in your little diapers? Just poop in the toilet!" he says.
Another parody inserts LaBeouf's speech into the latest Avengers movie.
This one makes him the centre of an infomercial.
And this Star Wars parody turned him into a hologramed and inserted him into the film.
LaBeouf, the star of the Transformers movie, is known for his peculiar art performances, having walked a red carpet with a paper bag over his head and live-streamed his own heartbeat.
And Franco is no stranger to defending these antics, penning an op-ed column for the New York Times in 2014 expressing empathy for LaBeouf's "erratic behaviour".