The film follows Mitch and Boyd as they embark a road trip to Chicago to retrieve Christmas presents after Boyd forgets to bring them to a family get together.
Naturally, chaos and hilarity ensues, with the pair knocking over a man dressed as Santa Claus and driving along with a mobile toilet on the back of their car.
The 63-year-old actor died in back August and this comedy is one of his final films.
He also completed work on Night at the Museum: Secret of the Tomb, Boulevard and Absolutely Anything before his death.
A Merry Friggin' Christmas will be released in cinemas and on-demand services on 7 November.