Five years on, Mike is a hovering helicopter father and husband and the family is none too thrilled with the status quo.
"For 20 years, he poured all his energy into his work; now he pours it all into us. Yay," says his wife (Breaking Bad's Betsy Brandt) with a marked lack of enthusiasm. So when he is offered his old TV news job by his former boss (Wendell Pierce from The Wire and Treme), he's encouraged by his exasperated nearest and dearest to accept.
No prizes for guessing whether he does or not.
In fact, based on the opening episode, there's not much about the show that's likely to surprise, given it's set up as a conventional family-based sitcom - it even comes complete with wacky neighbour (Mike's 40ish sister, who lives in the same apartment).
I imagine taking an old-fashioned approach to the series' structure was a conscious decision on the part of the programme-makers, given having a lead actor with such an obvious physical malady is pretty radical.
Inevitably, the way The Michael J Fox Show seeks to mainstream Parkinson's looks like it will shape up as its singular strength and central weakness.
In the series premiere, at least, Mike is constantly stopped by passersby and told what a hero he is because of his condition, an accolade it's clear that neither Fox nor the show have much patience for.
Instead, there's an insistent subtext that suffering from Parkinson's, or any other disease, does not come with a ticket to sainthood. As such, although Mike exhibits Fox's trademark energetic charisma, he can also be a bit of a jerk.
Mike asks for no sympathy, and he's certainly not offered any by his immediate family.
Indeed, his Parkinson's is the source of the opening episode's best quips: "Can you not have a personal victory right now?" says wife Annie as he struggles to serve dinner.
"We're starving."
However, if this is to develop into a satisfying series, rather than a well-meaning, long-form public service announcement, it will have to cast its net wider than just leaning on Mike's condition as a comic crutch.
The Michael J Fox Show debuts tomorrow night, 9pm, on Four.