Sykes said: "I couldn't believe he was still sitting there, like an a******. Shouldn't you be sitting there with a lawyer or LAPD, motherf*****?
"I hope he gets his s*** together. Until then, f*** him."
Sykes previously revealed that she "physically felt ill" after witnessing Smith's slap and was furious that he wasn't asked to leave.
She said of the actor, who has now been banned from the Oscars for 10 years: "And for them to let [Smith] stay in that room and enjoy the rest of the show and accept his award, I was like, 'How gross is this?' This sends the wrong message."
Sykes explained how Rock apologised to her following the incident as he knew it would overshadow the entire ceremony.
She recalled: "I saw Chris at [Guy Oseary's afterparty] and as soon as I walked up to him, the first thing he said is, 'I'm so sorry.' I was like, 'Why are you apologising?'
"He was like, 'It was supposed to be your night. You and Amy [Schumer] and Regina [Hall] were doing such a great job. I'm so sorry this is now gonna be about this'."