She immediately caught her mistake and corrected herself, adding: "'Excuse me."
The mistake was noticed and viewers quickly took to social media to share the error widely.
One viewer took the mistake as evidence of conspiracy and asked: "What happened to the pope and what do ITV news know?"
"That awkward moment when you accidentally report the death of the #pope on #itv. Guessing they have a preprepared script and the newsreader read on to that by mistake?'" another wrote.
Pope Francis, who is absolutely still here in spirit and flesh, used his annual Christmas address to ask for peace and equity in health care in the face of the pandemic.
"Grant health to the infirm and inspire all men and women of good will to seek the best ways possible to overcome the current health crisis and its effects," he said.
"Open hearts to ensure that necessary medical care – and vaccines in particular – are provided to those peoples who need them most."