"No morals, no obligation to truth, and I'm just left here, reading the lies, trying to protect my crew. Trying to remain calm. He did it," she told her fans without saying who "he" was.
Perrette seemed to imply that she had been assaulted, tweeting: "I've been supporting anti-bullying programs forever. But now I KNOW because it was ME!
"If it's school or work, that you're required to go to? It's horrifying. I left. Multiple Physical Assaults," she said.
"I REALLY get it now. Stay safe. Nothing is worth your safety. Tell someone."
Perrette also played Abby in crossover shows NCIS: Los Angeles and NCIS: New Orleans as well as original show JAG.
The actress studied criminal science before "accidentally" becoming an actress.
She announced she was leaving the show last October. At the time, it was publicly viewed as a professional decision.
Perrette played Abby Sciuto for 352 episodes of the series.
CBS yet to comment on the claims.