Ryanaddressed plastic surgery rumours late last year in an interview with Porter magazine.
"I don't pay a lot of attention frankly," she said of what's written about her.
"There's a lot of hatred in the world today, it's so easy to judge. Imagine being a hater, how stupid! My women friends are not sitting around talking about ... well, sometimes there are conversations like that, but the people I value talk about kids growing up, what kind of world they are going into, what we are eating, what we are breathing."
Meg Ryan shocked the Tony Awards with her 'new look'. Photo / AP
The reaction to Ryan's appearance at the Tony Awards is reminiscent of the public response to Renée Zellweger's strikingly different look in 2014 at the Elle Women in Hollywood Awards.
In response to the media scrutiny over her red carpet appearance at the Elle Awards, Zellweger, 45, told People, "I'm glad folks think I look different! I'm living a different, happy, more fulfilling life, and I'm thrilled that perhaps it shows.
"My friends say that I look peaceful. I am healthy.
"For a long time I wasn't doing such a good job with that. I took on a schedule that is not realistically sustainable and didn't allow for taking care of myself. Rather than stopping to recalibrate, I kept running until I was depleted and made bad choices about how to conceal the exhaustion. I was aware of the chaos and finally chose different things."
