In April last year, he described the task as one of his hardest challenges yet in an interview with the Daily Mirror: "It was tough going, I'm not going to lie. The dieting was pretty hardcore. I was losing seven pounds (3kg) every week. I'd have a Diet Coke, two egg whites in the morning, a piece of chicken, then another Diet Coke.
"That was rough. I got down to 143 pounds (65kg) and I was always hungry, and irritable. My body resembled a baby bird with its mouth open, crying, 'Feed me, feed me,' and you realise momma bird ain't going to feed you. It's hard."
McConaughey has scooped a number of industry accolades for Dallas Buyers Club already this year, including the Golden Globe and Critics Choice Award for Best Actor and the Screen Actors Guild Award for Outstanding Male Actor in a Leading Role.
These recent wins have put him in a strong position ahead of the Oscars on 2 March, the nominations for which were announced last Thursday.
McConaughey's Dallas Buyers Club co-star, Jared Leto, is also nominated for his performance as the HIV positive transgender woman Rayon. The film itself has been shortlisted for Best Picture and Best Original Screenplay.
- Independent