"It's even more of a blow because he allows Jacqui [Ainsley, his stepmother] and Guy to still follow him and he follows them back. Hopefully this is just a teenage teething problem."
The news that Rocco has deleted his account comes amid claims Guy has hired a lawyer to fight for custody of his son.
Rocco, is keen to live in London full-time with his father and defied a recent court order to return to New York to be with his mother, and the director is doing his best to support the teenager's position.
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According to TMZ, Rocco - and his father - feel he has a more "stable and loving" home life with Guy, his wife Jacqui and their three children, Rafael, four, Rivka, three, and Levi, 18 months.
The teenager thinks his Like a Virgin singer mother is "too controlling" and doesn't pay him any real attention.
Because of Rocco's strong views, Guy has now hired a lawyer and is preparing for a legal battle to keep custody of his son, who left Madonna's tour a month ago and refused to return to her for Christmas.
A New York judge has ordered Rocco back to the US for a hearing next month.
-Bang! Showbiz