Andres was a huge success in her own right. finding fame in the art and film world. She was best known for her 1996 film Black Kites — which Lucian starred in.
The film is about the survival of an artist during the siege of Sarajevo.
She was also known for her experimental performance art.
Actor James Woods shared his condolences on Twitter:
"Condolences to Steve Buscemi and loved ones on his loss. This fine family was so supportive of first responders during 9/11 tragedy," he wrote.
Steve Buscemi’s wife Jo Andres, filmmaker and choreographer, dies age 65 // Condolences to Steve Buscemi and loved ones on his loss. This fine family was so supportive of first responders during 9/11 tragedy. #RIPJoAndreshttps://t.co/39tpAq5Bvk
It's understood Andres had a crush on Buscemi when she was a teenager, but she didn't recognise him when they first met.
The Boardwalk Empire star said when they had finally crossed paths, it took a bit for things to 'click'.
"When we met, she didn't realise I was the guy on the poster. When we got to my apartment, she saw the same poster and said, 'That's you!'" he has said previously.
The couple had not been seen on the red carpet together since mid 2018.
Just heard the tragic news about Jo Andres Buscemi. She was absolutely one of the loveliest people,and she and Steve had a real love story. What a shame. Just heartbreaking.