The new most popular picture showed the 23-year-old singer wearing a red top and staring directly at the camera as she sips the carbonated beverage through a striped straw.
Referring to the fact her song Me & the Rhythm is quoted on the bottle as part of the drinks company's 'Share a Coke and a Song' campaign, Selena captioned the post: "when your lyrics are on the bottle."
Prior to Gomez and Bieber's record-breaking photos, the most liked photo was a 2015 image of Kendall Jenner with her hair formed into hearts that had attracted 3.6 million likes.
Gomez recently admitted she is "done" talking about her on/off relationship with Bieber, who she was with from 2011 to 2014.
She said: "At first I didn't care. To me it was: I'm 18, I have a boyfriend, we look cute together, we like that. Then I got my heart broken and I cared.
"Because people had no idea what was going on, but everywhere it was a million different things. I was kind of in a corner, banging my head against the wall. I didn't know where to go," she said.
"I'm so exhausted. I honestly am so done. I care about his health and well-being. But I can't do it anymore."
- Bang! Showbiz