"The papers were like, 'George Clooney is Il Divo!' It was a horrible story," Clooney laughed.
He was on the receiving end on this occasion, but usually it's Clooney who pulls the pranks on his co-stars.
One of his best was on Matt Damon when they were filming The Monuments Men. Clooney told the wardrobe department to take in the waist of Damon's pants every couple of days, tricking the actor into thinking he was putting on weight.
"It was just funny because he showed up on the set, Matt looks great," Clooney told E! News. "He shows up on the set, he's like 'I wanna lose 15 pounds (6kg) on this movie.'
"So he's dieting and exercising. He would go away for a week and I would just have the wardrobe people take in his wardrobe half an inch. By the end, he's just like eating a grape but his pants are getting tighter," Clooney laughed.
Damon didn't find out he'd been pranked until after the movie finished shooting.